Skip Navigation


Mathematical Medicine and Biology Advance Access originally published online on May 29, 2008
Mathematical Medicine and Biology 2008 25(2):113-131; doi:10.1093/imammb/dqn006
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
25/2/113    most recent
dqn006v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Wirth, B.
Right arrow Articles by Sobey, I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wirth, B.
Right arrow Articles by Sobey, I.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The author 2008. Published by Oxford University Press on behalf of the Institute of Mathematics and its Applications. All rights reserved.

A model for an inverse power constitutive law for cerebral compliance

Benedikt Wirth and Ian Sobey{dagger}

Computing Laboratory, University of Oxford, Wolfson Building, Parks Road, Oxford OX1 3QD, UK

{dagger} Email: ian.sobey{at}comlab.ox.ac.uk

Received on May 17, 2007. Revised on December 11, 2007. Accepted on March 10, 2008.

This work provides a model that links the commonly used inverse power relationship between cerebral compliance and intracranial pressure to some mechanical properties of distal cerebral veins. The underlying model of the compliance is based on a mechanism whereby the distal cerebral blood vessels are assumed to be the main compliant part of the brain and cerebrospinal fluid volume changes are accommodated by blood displacement into or out of these vessels. This simplified model is not intended to produce a highly accurate prediction of the intracranial pressure–volume curve, which is best achieved by a numerical solution of more complicated models, but rather to justify the phenomenological inverse power law and to provide a basic interpretation of cerebral elasticity, reference pressure and exponent of the constitutive law in terms of underlying mechanical parameters.

Keywords: brain compliance; constitutive law; cerebral elasticity


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.